Abstract:
Modern biological physics has been significantly advanced recently with rapid developments of various physical techniques and molecular biology methods. Complex biological machinery can be investigated at the most fundamental level and thus molecular mechanisms are elucidated. Here, we present our recent studies of several important biological systems by integrating femtosecond spectroscopy and site-directed mutations. We are able to map out the entire evolution of biological dynamics in real time and reveal their molecular mechanisms with unprecedented details.

Education
1999 Ph.D. Chemical Physics, California Institute of Technology
　　Advisor: Nobel Laureate, Linus Pauling Professor Ahmed H. Zewail
1994 M.S. Physical Chemistry, Kansas State University
　　Advisor: University Distinguished Professor Donald W. Setser
1988 M.S. Laser Physics, Huazhong University of Science and Technology
　　Advisor: Professor Zaiguang Li
1985 B.S. Laser Physics, Huazhong University of Science and Technology

Appointments
2010- Robert Smith Professor of Physics, The Ohio State University
2010- Professor of Chemistry and Biochemistry, The Ohio State University
2007-2010 Robert Smith Associate Professor of Physics, The Ohio State University
2007-2010 Associate Professor of Chemistry and Biochemistry, The Ohio State University
2002-2007 Assistant Professor
　　　　　Department of Physics, The Ohio State University
　　　　　Department of Chemistry and Biochemistry, The Ohio State University
　　　　　Member of OSU Biophysics, Chemical Physics, and Biochemistry Programs, Spectroscopy Institute, The Ohio State University
2011-2014 Visiting Professor, Harbin Institute of Technology
2010 Visiting Associate, California Institute of Technology
2002- Guest Professor, Huazhong University of Science and Technology
1999-2002 Postdoctoral Fellow, NSF Laboratory for Molecular Sciences, California Institute of Technology, Research Advisor: Professor Ahmed H. Zewail

Honors and Awards
2013 Guggenheim Fellowship, The John Simon Guggenheim Memorial Foundation
2011 Fellow, The American Association for the Advancement of Science (AAAS)
2009 Fellow, The American Physics Society (APS)
2009 Outstanding Young Researcher Award, The Overseas Chinese Physics Association
2008 Camille Dreyfus Teacher-Scholar Award, The Camille and Henry Dreyfus Foundation
2008 Dr. Elizabeth L. Gross Award for Faculty Excellence, The Ohio State University
2008 CAREER Award, The National Science Foundation
2008 Sloan Research Fellowship, The Alfred P. Sloan Foundation
2007 Robert Smith Professorship, The Ohio State University
2005 Packard Fellowship, The David and Lucile Packard Foundation
1999 Milton and Francis Clauser Doctoral Prize, California Institute of Technology
1999 The Herbert Newby McCoy Award, California Institute of Technology

Research Interests
Femtobiology (DNA repair, Circadian rhythm, Photoreceptors)
Biomolecular Recognition (Hydration dynamics, Conformation fluctuations)
Ultrafast Protein/Enzyme Dynamics (Heme proteins, Flavoproteins)
Four Dimensional Electron Diffraction and Microscopy for Biology (Structure, Dynamics and Function)